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The Only Place in the World That Cures Neurogenic Bladder

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Xiao Procedure for Patients with Spinal Cord Injuries and Paraplegia:

An Effective Surgical Solution for Urinary and Fecal Incontinence

Nerve growth typically takes about 8 months to a year (depending on individual circumstances). Successful neuroanastomosis results in restored bladder function, enabling independent voiding and addressing urinary incontinence issues in spinal cord injury patients.

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What can we do?

About 20 million people globally have spinal cord injuries (SCI), including those who are paraplegic. Each year, around 1 million more people get these injuries[1]. In the U.S., as many as 450,000 people have an SCI, says the National Spinal Cord Injury Association[2]. More than 80% of these people have some trouble with bladder control, known as neurogenic bladder, which is a common challenge for those with paraplegia.

Treatment with the Xiao procedure, Nerve growth typically takes about 8 months to a year (depending on individual circumstances). Successful neuroanastomosis leads to restored bladder function, allowing independent voiding and addressing urinary incontinence problems in spinal cord injury patients.

  • We are the world's only hospital with a proven full cure for neurogenic bladder.

  • Advanced treatment options for neurogenic bladder in spinal cord injury patients.

  • Exclusive and specialized care for paraplegic patients' bladder issues, with over 1,000 successful cases.

What is the Spinal Cord Injury Program at Xiao Chuan-Guo Hospital?

Spinal cord injuries often result from accidents like falls from heights, heavy object impacts, or car crashes, leading to incomplete or complete (paralysis) injuries. Complications and harms include:

  • (1) Urinary dysfunction: Damage to nerves controlling the bladder after spinal cord injury or severance hinders conscious control of urination, causing urinary dysfunction or incontinence.

  • (2) Fecal function impairment: Paralysis resulting from spinal cord injury damages nerves controlling the rectum, leading to loss of voluntary control over the anal sphincter and rectal defecation reflex, causing constipation or fecal incontinence, with constipation being most common in paralyzed patients.

  • (3) Urinary system infections and kidney damage: Nerve dysfunction in controlling the bladder leads to weak bladder muscles, bladder paralysis, urinary retention, and recurrent urinary tract infections. Prolonged infections, with urine unable to be expelled leading to kidney damage, can result in kidney failure, uremia.

  • (4) Lower limb motor and sensory function impairments: Paralyzed patients are prone to pressure sores and osteomyelitis, leading to secondary infections and even septicemia.

The majority of spinal cord injury patients die from complications such as urinary tract infections, respiratory infections, pressure sores, and kidney failure. Effective treatment and a conducive recovery environment can not only prolong survival but also enable patients to return to work, highlighting the importance of preventing and treating complications.

Xiao Procedure for Treating Neurogenic Bladder in Spinal Cord Injury Patients:

Xiao procedure involves cutting a part of a nerve that controls lower limb movement (L5 anterior root) and linking it to the nerve that controls the bladder detrusor muscle (S2 and/or S3 anterior roots). This establishes a new nerve pathway through the “skin-spinal cord-central nervous system-bladder reflex arc.” Stimulating the skin area controlled by the L5 posterior root sends signals from the L5 anterior root to the bladder, prompting the detrusor muscle to contract, aiding controlled urination.

Recovery and Outcomes Post-Treatment:

Nerve growth typically takes about 8 months to a year (depending on individual circumstances). Successful neuroanastomosis results in restored bladder function, enabling independent voiding and addressing urinary incontinence issues in spinal cord injury patients.

Neurogenic Bladder in Patients with Spinal Cord Injury and Paraplegia

Understanding Bladder Management After Spinal Cord Injury

When someone injures their spinal cord, it can mess up how their bladder works. This might happen because of an accident, a disease, or if the spinal cord doesn’t get enough blood. This injury can cause bladder infections or problems with kidneys and peeing. After such an injury, it’s really important to take care of the bladder. The care needed can change depending on who you are, your daily habits, if your hands work well, and if you can see a doctor easily. Good care means fewer problems and a better life.

A lot of people with spinal cord injuries find it hard to control their bladder. Everyone is different, so they need their own plan for care, and they might have to go to the doctor a lot. Many end up in the hospital or a nursing home because of bladder issues.

Normally, our brain tells our bladder when to hold pee and when to let it go. If the spinal cord is hurt, it can’t send these messages right. Right after a big injury, the body can be in shock, and the bladder doesn’t work. The person can’t feel when it’s time to pee and might need a tube, called a catheter, to help them.

If the injury is high up on the spine, the bladder might start working again but without control. So, you might feel when it’s full but can’t stop the pee. This can be bad for the kidneys if it’s not taken care of.

If the injury is lower down, near the hips, the bladder and muscles might get too loose. If it’s a complete injury, the person can’t feel when the bladder is full and can’t pee by themselves. This can mean a bladder that doesn’t squeeze and muscles that don’t relax as they should, maybe because the nerves are damaged.

Complications of Neurogenic Bladder

People with spinal cord injuries  often have bladder problems called neurogenic bladder. The most common issues are urinary tract infections, bladder stones, and kidney damage. These problems are related to the bladder not working right or from using tubes, called catheters, to drain urine.

People with SCI get urinary infections often. Studies show that using coated catheters can lower the risk of infections compared to regular PVC catheters. Taking antibiotics all the time to prevent infections doesn’t work well for SCI patients and can lead to the antibiotics not working anymore. Other treatment plans might help reduce this problem.

Some treatments to lower infection risk include using a medicine called me-henamine or cranberry pills every day. But for people with SCI who have stable bladder care, these don’t seem to stop infections. An interesting way to prevent infections is to put a harmless type of E. coli bacteria into the bladder.

Problems like urethritis and prostatitis can be lessened by using catheters only sometimes. Testicle and epididymis infections are often linked to catheters and are treated with antibiotics. Bladder and kidney stones happen because of infections, long-term catheters, and not emptying the bladder fully. The risk of bladder cancer is 20 times higher in people with SCI, and the most common type is squamous cell cancer.

A condition called autonomic dysreflexia causes high blood pressure, slow heart rate, and sweating. It happens in people with SCI above the T6 level and is a medical emergency.

Other Serious Complications of Spinal Cord Injury

Spinal cord injury can cause urinary retention and severe hydronephrosis.

  • Urinary retention, the inability to fully empty the bladder during urination, can occur due to disrupted nerve signals in SCI. This leads to urine build-up in the bladder, causing discomfort and raising the risk of urinary tract infections.

  • Severe hydronephrosis is the kidneys’ excessive swelling from blocked urine flow in the drainage system. In SCI cases, nerve damage affects normal urinary system function, hindering kidney drainage and causing urine accumulation, leading to hydronephrosis.

Both urinary retention and severe hydronephrosis are serious SCI complications needing medical attention to prevent further issues and maintain urinary health.

Conservative Management

The standard care for managing a neurogenic bladder includes educating the patient, following a urination schedule, using techniques like Valsalva and Credé, medication, intermittent catheterization, or leaving a drainage tube. Regular bladder emptying is crucial to prevent infections, upper urinary system damage, and leaks.

For individuals with spinal cord injuries, intermittent catheterization is preferred for urination. Leaving a catheter in place can increase the risk of infections, kidney damage, and other complications. Anticholinergic medications are commonly used to treat an overactive bladder muscle, improving bladder function and quality of life with varying side effects.

In the long run, conservative management acts as an ongoing risk-reduction strategy, with patients facing largely irreversible symptoms. Patients and healthcare providers are inclined to consider surgical interventions for better outcomes, especially for those at higher risk of complications.

Traditional Surgical Management

  1. Bladder Atony Procedure: A 2cm bladder puncture below the navel to drain residual urine from the bladder by leaving a catheter in place.

  2. Indwelling Catheterization: Draining residual urine from the bladder by placing a catheter through the urethra.

  3. Intermittent Catheterization: Periodically inserting a catheter through the urethra to drain residual urine from the bladder.

Post-Treatment Outcomes: Traditional treatment methods focus on draining residual urine from the bladder to prevent kidney hydronephrosis and urinary tract infections. However, prolonged use of catheters or drainage tubes can lead to bladder spasms, urinary tract infections, and stones. These treatment methods can only partially improve patients’ lives, prevent further complications, prolong life, but cannot fundamentally resolve the issues of urinary dysfunction.

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