top of page

神経因性膀胱を治療できる世界で唯一の場所

xiao 手順 process1.webp

脊髄損傷および下半身麻痺患者に対するシャオ手術:

尿失禁と便失禁に対する効果的な外科的治療

神経の成長には通常約 8 か月から 1 年かかります (個人の状況によって異なります)。神経吻合が成功すると膀胱機能が回復し、脊髄損傷患者の自力排尿が可能になり、尿失禁の問題に対処できるようになります。

神経因性膀胱..webp

私たちは何ができる?

脊髄損傷(SCI)を患っている人は世界で約2,000万人おり、下半身麻痺の人もその1人です。毎年、約100万人が新たに脊髄損傷を負っています[ 1 ]。米国脊髄損傷協会によると、米国では45万人もの人がSCIを患っています[ 2 ]。これらの人々の80%以上が、神経因性膀胱と呼ばれる膀胱のコントロールに何らかの問題を抱えており、下半身麻痺の人々によく見られる問題です。

シャオ手術による治療では、神経の成長には通常約 8 か月から 1 年かかります (個人の状況によって異なります)。神経吻合が成功すると膀胱機能が回復し、脊髄損傷患者の自主的な排尿が可能になり、尿失禁の問題に対処できます。

  • We are the world's only hospital with a proven full cure for neurogenic bladder.

  • Advanced treatment options for neurogenic bladder in spinal cord injury patients.

  • Exclusive and specialized care for paraplegic patients' bladder issues, with over 1,000 successful cases.

小川国病院の脊髄損傷プログラムとは何ですか?

脊髄損傷は、高所からの落下、重い物体との衝突、自動車事故などの事故によって起こることが多く、不完全損傷または完全損傷(麻痺)につながります。合併症や害には次のものがあります。

  • (1)排尿機能障害:脊髄損傷または脊髄切断後に膀胱を制御する神経が損傷し、排尿の意識的な制御が妨げられ、排尿機能障害または失禁を引き起こします。

  • (2)排便機能障害:脊髄損傷による麻痺により直腸を制御する神経が損傷し、肛門括約筋および直腸排便反射の自発的制御が失われ、便秘または便失禁を引き起こします。麻痺患者では便秘が最も一般的です。

  • (3)尿路感染症および腎臓障害:膀胱を制御する神経の機能障害により、膀胱筋の衰弱、膀胱麻痺、尿閉、再発性尿路感染症が発生します。感染が長期化すると、尿を排出できずに腎臓障害を引き起こし、腎不全、尿毒症を引き起こす可能性があります。

  • (4)下肢の運動機能および感覚機能障害:麻痺患者は褥瘡や骨髄炎を起こしやすく、二次感染や敗血症を引き起こすこともあります。

脊髄損傷患者の多くは、尿路感染症、呼吸器感染症、褥瘡、腎不全などの合併症で亡くなっています。効果的な治療と回復に適した環境があれば、生存期間を延ばせるだけでなく、患者の職場復帰も可能になるため、合併症の予防と治療の重要性が強調されます。

脊髄損傷患者の神経因性膀胱を治療するためのXiao手術:

シャオ手術では、下肢の動きを制御する神経(L5前根)の一部を切断し、それを膀胱排尿筋を制御する神経(S2および/またはS3前根)につなげます。これにより、「皮膚-脊髄-中枢神経系-膀胱反射弓」を通る新しい神経経路が確立されます。L5後根によって制御される皮膚領域を刺激すると、L5前根から膀胱に信号が送られ、排尿筋が収縮して排尿のコントロールが促進されます。

治療後の回復と結果:

神経の成長には通常約 8 か月から 1 年かかります (個人の状況によって異なります)。神経吻合が成功すると膀胱機能が回復し、脊髄損傷患者の自力排尿が可能になり、尿失禁の問題に対処できるようになります。

脊髄損傷および下半身麻痺患者における神経因性膀胱

脊髄損傷後の膀胱管理について理解する

When someone injures their spinal cord, it can mess up how their bladder works. This might happen because of an accident, a disease, or if the spinal cord doesn’t get enough blood. This injury can cause bladder infections or problems with kidneys and peeing. After such an injury, it’s really important to take care of the bladder. The care needed can change depending on who you are, your daily habits, if your hands work well, and if you can see a doctor easily. Good care means fewer problems and a better life.

A lot of people with spinal cord injuries find it hard to control their bladder. Everyone is different, so they need their own plan for care, and they might have to go to the doctor a lot. Many end up in the hospital or a nursing home because of bladder issues.

Normally, our brain tells our bladder when to hold pee and when to let it go. If the spinal cord is hurt, it can’t send these messages right. Right after a big injury, the body can be in shock, and the bladder doesn’t work. The person can’t feel when it’s time to pee and might need a tube, called a catheter, to help them.

If the injury is high up on the spine, the bladder might start working again but without control. So, you might feel when it’s full but can’t stop the pee. This can be bad for the kidneys if it’s not taken care of.

If the injury is lower down, near the hips, the bladder and muscles might get too loose. If it’s a complete injury, the person can’t feel when the bladder is full and can’t pee by themselves. This can mean a bladder that doesn’t squeeze and muscles that don’t relax as they should, maybe because the nerves are damaged.

神経因性膀胱の合併症

People with spinal cord injuries  often have bladder problems called neurogenic bladder. The most common issues are urinary tract infections, bladder stones, and kidney damage. These problems are related to the bladder not working right or from using tubes, called catheters, to drain urine.

People with SCI get urinary infections often. Studies show that using coated catheters can lower the risk of infections compared to regular PVC catheters. Taking antibiotics all the time to prevent infections doesn’t work well for SCI patients and can lead to the antibiotics not working anymore. Other treatment plans might help reduce this problem.

Some treatments to lower infection risk include using a medicine called me-henamine or cranberry pills every day. But for people with SCI who have stable bladder care, these don’t seem to stop infections. An interesting way to prevent infections is to put a harmless type of E. coli bacteria into the bladder.

Problems like urethritis and prostatitis can be lessened by using catheters only sometimes. Testicle and epididymis infections are often linked to catheters and are treated with antibiotics. Bladder and kidney stones happen because of infections, long-term catheters, and not emptying the bladder fully. The risk of bladder cancer is 20 times higher in people with SCI, and the most common type is squamous cell cancer.

A condition called autonomic dysreflexia causes high blood pressure, slow heart rate, and sweating. It happens in people with SCI above the T6 level and is a medical emergency.

脊髄損傷のその他の重篤な合併症

Spinal cord injury can cause urinary retention and severe hydronephrosis.

  • Urinary retention, the inability to fully empty the bladder during urination, can occur due to disrupted nerve signals in SCI. This leads to urine build-up in the bladder, causing discomfort and raising the risk of urinary tract infections.

  • Severe hydronephrosis is the kidneys’ excessive swelling from blocked urine flow in the drainage system. In SCI cases, nerve damage affects normal urinary system function, hindering kidney drainage and causing urine accumulation, leading to hydronephrosis.

Both urinary retention and severe hydronephrosis are serious SCI complications needing medical attention to prevent further issues and maintain urinary health.

保守的な管理

The standard care for managing a neurogenic bladder includes educating the patient, following a urination schedule, using techniques like Valsalva and Credé, medication, intermittent catheterization, or leaving a drainage tube. Regular bladder emptying is crucial to prevent infections, upper urinary system damage, and leaks.

For individuals with spinal cord injuries, intermittent catheterization is preferred for urination. Leaving a catheter in place can increase the risk of infections, kidney damage, and other complications. Anticholinergic medications are commonly used to treat an overactive bladder muscle, improving bladder function and quality of life with varying side effects.

In the long run, conservative management acts as an ongoing risk-reduction strategy, with patients facing largely irreversible symptoms. Patients and healthcare providers are inclined to consider surgical interventions for better outcomes, especially for those at higher risk of complications.

伝統的な外科的治療

  1. Bladder Atony Procedure: A 2cm bladder puncture below the navel to drain residual urine from the bladder by leaving a catheter in place.

  2. Indwelling Catheterization: Draining residual urine from the bladder by placing a catheter through the urethra.

  3. Intermittent Catheterization: Periodically inserting a catheter through the urethra to drain residual urine from the bladder.

Post-Treatment Outcomes: Traditional treatment methods focus on draining residual urine from the bladder to prevent kidney hydronephrosis and urinary tract infections. However, prolonged use of catheters or drainage tubes can lead to bladder spasms, urinary tract infections, and stones. These treatment methods can only partially improve patients’ lives, prevent further complications, prolong life, but cannot fundamentally resolve the issues of urinary dysfunction.

bottom of page